The globules are intrahepatic collections of alpha-1-antitrypsin that is not being excreted from the hepatocytes.
肝细胞未排泌的α-1-抗胰蛋白酶在肝内聚集,形成小球。
Alpha 1-antitrypsin deficiency is a genetically transmitted disorder associated with an increased risk of emphysema and liver disease.
阿尔法1 -抗胰蛋白酶缺乏症是一种遗传疾病传播有关的风险增加肺气肿和肝脏疾病。
Viral hepatitis (B or C) is the most common cause for macronodular cirrhosis. Wilson's disease and alpha-1-antitrypsin deficiency also can produce a macronodular cirrhosis.